MAPED¶

MAPED (multi-angle precession electron diffraction) is an open-source experimental and computational approach for generating 4D-STEM datasets that offer many of the advantages of precession experiments without requiring dedicated hardware. Multiple datasets are acquired at different beam tilts and computationally combined during post-processing.
Authors: S. M. Ribet*, R. Dhall*, C. Ophus, K. C. Bustillo
Links: Source code · Paper
quantEM¶

quantEM is a quantitative electron microscopy data analysis toolkit built on PyTorch. It brings together tools for reconstructing or analyzing a wide range of transmission electron microscopy (TEM) techniques, including nanobeam diffraction, phase retrieval, real-space imaging and tomography, spectroscopy, and related analyses within a consistent, GPU-accelerated API.
Links: Source code · Tutorials
py4DSTEM¶

py4DSTEM is an open-source set of Python tools for processing and analyzing four-dimensional scanning transmission electron microscopy (4D-STEM) data, including nanobeam and large-convergence-angle diffraction data. It includes workflows for strain, phase, and orientation mapping; phase retrieval; kinematical and dynamical simulations; flowline analysis; and related modules, with tutorials covering common analysis patterns.
Links: Source code · Tutorials · Paper · Phase retrieval paper
- Ribet, S. M., Dhall, R., Ophus, C., & Bustillo, K. C. (2025). Multi-angle Precession Electron Diffraction (MAPED): A Versatile Approach to 4D-STEM Precession. Microscopy and Microanalysis, 31(6). 10.1093/mam/ozaf103
- Savitzky, B. H., Zeltmann, S. E., Hughes, L. A., Brown, H. G., Zhao, S., Pelz, P. M., Pekin, T. C., Barnard, E. S., Donohue, J., Rangel DaCosta, L., Kennedy, E., Xie, Y., Janish, M. T., Schneider, M. M., Herring, P., Gopal, C., Anapolsky, A., Dhall, R., Bustillo, K. C., … Ophus, C. (2021). py4DSTEM: A Software Package for Four-Dimensional Scanning Transmission Electron Microscopy Data Analysis. Microscopy and Microanalysis, 27(4), 712–743. 10.1017/s1431927621000477
- Varnavides, G., Ribet, S. M., Zeltmann, S. E., Yu, Y., Savitzky, B. H., Byrne, D. O., Allen, F. I., Dravid, V. P., Scott, M. C., & Ophus, C. (2023). Iterative Phase Retrieval Algorithms for Scanning Transmission Electron Microscopy. arXiv. 10.48550/ARXIV.2309.05250